3,3-Dimethylcyclohexyl methyl ketone
| Common Name: |
3,3-Dimethylcyclohexyl methyl ketone |
| IUPAC Name: |
1-(3,3-dimethylcyclohexyl)ethanone |
| Molecular Formula: |
C10H18O |
| SMILES: |
CC(=O)C1CCCC(C1)(C)C |
| Inchi: |
1S/C10H18O/c1-8(11)9-5-4-6-10(2,3)7-9/h9H,4-7H2,1-3H3 |
| Inchi Key: |
DXIWBWIDAYBUDF-UHFFFAOYSA-N |
| Cas No: |
25304-14-7 |
| Name |
Value |
| Lipinski Violations |
0 |
| Ghose Violations |
1 |
| Veber Violations |
0 |
| Egan Violations |
0 |
| Muegge Violations |
2 |
| Name |
Value |
| Molecular Weight (g/mol) |
154.25 |
| Mass (g/mol) |
154.136 |
| Molar Refractivity |
48.01 |
| Net Charge |
|
| HBD |
|
| HBA |
1 |
| Rt Bonds |
1 |
| Rings |
1 |
| TPSA |
17.07 |
| Hetero Atoms |
1 |
| Heavy Atoms |
11 |
| Aromatic Heavy Atoms |
0 |
| Melting Point (°C) |
|
| Boiling Point (°C@760.00mm Hg) |
202.8 |
| Vapor Pressure (mmHg@25.00 °C) |
0.287 |
| Vapor Density (Air =1) |
|
| Fraction Csp3 |
0.90 |
| LogP |
2.792 |
| iLOGP |
2.34 |
| XLOGP3 |
2.68 |
| WLOGP |
2.79 |
| MLOGP |
2.30 |
| ESOL Log S |
-2.42 |
| ESOL Solubility (mg/ml) |
0.588 |
| ESOL Solubility (mol/l) |
0.004 |
| ESOL Class: esol_class |
Soluble |
| Ali Log S |
-2.69 |
| Ali Solubility (mg/ml) |
0.31 |
| Ali Solubility (mol/l) |
0 |
| Ali Class |
Soluble |
| Silicos-IT LogSw |
-2.40 |
| Silicos-IT Solubility (mg/ml) |
0.61 |
| Silicos-IT Solubility (mol/l) |
0 |
| Silicos-IT Class |
Soluble |
| Name |
Value |
| GI Absorption |
High |
| BBB Permeable |
1 |
| PgP Substrate |
0 |
| Log Kp (cm/s) |
-5.34 |
| Bioavailability Score |
0.55 |
| Caco2 |
1 |
| Human Intestinal Absorption |
1 |
| Plasm Protein Binding |
1.072 |
| CYP1A2 Inhibitor |
0 |
| CYP2C19 Inhibitor |
0 |
| CYP2C9 Inhibitor |
0 |
| CYP2D6 inhibitor |
0 |
| CYP3A4 inhibitor |
0 |
| Ames mutagenesis |
0 |
| Acute Oral Toxicity |
1.984 |
| Carcinogenicity (Binary) |
0 |
| Carcinogenicity (Trinary) |
Non-required |
| Eye Irritation |
1 |
| Hepatotoxicity |
0 |
| Androgen Receptor Binding |
0 |
| Aromatase Binding |
0 |
| Estrogen Receptor Binding |
0 |
| Glucocorticoid Receptor Binding |
0 |
| Thyroid Receptor Binding |
0 |
| BRCP inhibitor |
0 |
| BSEP inhibitor |
0 |
| OATP1B1 inhibitor |
1 |
| OATP1B3 inhibitor |
1 |
| OATP2B1 inhibitor |
0 |
| OCT1 inhibitor |
0 |
| OCT2 inhibitor |
0 |
